Combining Raman spectroscopy and optical coherence tomography increases diagnostic accuracy.

Colorectal cancer is one of the most common cancers worldwide. It is usually diagnosed during a colonoscopy, in which suspicious areas are examined and tissue samples are taken. To reduce the number of unnecessary biopsies and improve diagnostics, researchers are increasingly turning to optical methods.

David L. Vasquez has now published a clinical study combining two modern methods: Raman spectroscopy (RS), which provides molecular information about the tissue, and optical coherence tomography (OCT), which makes the tissue structure visible in three dimensions. Both methods were tested using specially developed fiber optic probes.

The results impressively demonstrate that combining independent optical methods can significantly improve cancer diagnostics. In the long term, this approach could help make colorectal cancer screening more precise, gentler, and more efficient.

We congratulate David L. Vasquez on this important publication!

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• Journal: International Journal of Molecular Sciences (IJMS)